Molecular and Translational Toxicology (MATT)
Date |
Title |
Lecturer |
Content |
|
1 | 9/4 | Basic Concepts in Translational Toxicology | Vishal S. Vaidya | Overview, Definitions, Importance in drug development, environmental health and patient care, fundamental concepts, techniques used. |
2 | 9/9 | Pharmacodynamics | David Golan | Drug receptor interactions, agonists, antagonists, pharmacogenomics |
3 | 9/11 | Pharmacokinetics | David Golan | Absorption, Distribution, Metabolism, Excretion |
4 | 9/16 | Biology of the Normal vs Abnormal Cell | Jagesh V. Shah | Structure/function of cell and cellular components, Mitochondria, ER & Nucleus as targets of Toxicants |
5 | 9/18 | Biotransformation | Sujal Deshmukh | Bioactivation, Detoxification, Factors affecting susceptibility |
6 | 9/23 | Genetic Toxicity & Carcinogenesis | Alan D'Andrea | DNA damage, Mutation, DNA repair, Initiation & Progression in Carcinogenesis |
7 | 9/25 | Epigenetics and Toxicology |
Bernardo Lemos |
Definition, Methylation, Histone Modifications, Non Coding RNA, Genomic Imprinting |
9/30 | EXAM 1 | |||
8 | 10/2 | Brain Toxicology | Francisco Quintana |
|
9 | 10/7 | Lung Toxicology | David Christiani |
|
10 | 10/9 | Liver Toxicology | Vishal Vaidya | |
10/14 | COLUMBUS DAY | |||
11 | 10/16 | Nano Toxicology | Philip Demokritou | |
12 | 10/21 | Pesticides | Alan Woolf | |
13 | 10/23 | Heart Toxicology | James Januzzi | |
14 | 10/28 | Metal Toxicology | Marc Weisskopf | |
15 | 10/30 | Endocrine Disruptors | Joseph Braun | |
16 | 11/4 | Kidney Toxicology | Oana Nicoara | |
17 | 11/6 | Drugs of Abuse | Chris Rosenbaum and Rick Church |
|
11/11 | VETERANS DAY | |||
11/13 | EXAM 11 | |||
17 | 11/18 | Toxicology in Therapeutic Development | Nicole Hurst & Paul Nugent | |
18 | 11/20 | Toxicity Monitoring Post Marketing | Jerry Avorn | |
19 | 11/25 | Mitigation of Toxicity | Eva Guinan | Example of drug effective against radiation toxicity |
20 | 11/27 | Stem Cells for Toxicity Screening | Benjamin Freedman | ES cells, iPS cells, Directed Differentiation, Protocols, Toxicology Application |
21 | 12/2 | Translational Technologies for Toxicology | Anthony Bahinski | Organs on a Chip, Principles, Challenges and Applications |
22 | 12/4 | Zebrafish an Integrative Model for Toxicity Screening | Wolfram Goessling | |
12/9 |
Grant Writing, Review and Defense | |||