September 2015 archive

Kidney toxicity screening tool developed by grantee and NTP team

A team of researchers, including NIEHS grantees and National Toxicology Program (NTP) scientists, developed the first method to test for kidney toxicity using high throughput screening (HTS). Because drugs and environmental chemicals can cause injury to kidneys, the new test could help reduce a significant health burden for patients and decrease the financial risk for pharmaceutical and chemical companies.

The team, led by Vishal Vaidya, Ph.D. , of Harvard Medical School, and including molecular toxicologist Scott Auerbach, Ph.D., from NTP, published their approach Aug. 10 in the Journal of the American Society of Nephrology. “This high-throughput assay allows, for the first time, rapid and robust screening of kidney toxic compounds, to support chemical risk assessment and facilitate elimination of drug candidates early in the process before they reach humans,” Vaidya said.

Environmental Factor, September 2015 (a newsletter of NIH/NIEHS)

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Posted by Vishal Vaidya on Thu, 3 Sep 2015